AUTHOR=Berger Daniel R. , Seung H. Sebastian , Lichtman Jeff W. TITLE=VAST (Volume Annotation and Segmentation Tool): Efficient Manual and Semi-Automatic Labeling of Large 3D Image Stacks JOURNAL=Frontiers in Neural Circuits VOLUME=12 YEAR=2018 URL=https://www.frontiersin.org/journals/neural-circuits/articles/10.3389/fncir.2018.00088 DOI=10.3389/fncir.2018.00088 ISSN=1662-5110 ABSTRACT=

Recent developments in serial-section electron microscopy allow the efficient generation of very large image data sets but analyzing such data poses challenges for software tools. Here we introduce Volume Annotation and Segmentation Tool (VAST), a freely available utility program for generating and editing annotations and segmentations of large volumetric image (voxel) data sets. It provides a simple yet powerful user interface for real-time exploration and analysis of large data sets even in the Petabyte range.