AUTHOR=Stokes Caleb C. A. , Teeter Corinne M. , Isaacson Jeffry S. 

TITLE=Single dendrite-targeting interneurons generate branch-specific inhibition

JOURNAL=Frontiers in Neural Circuits

VOLUME=8

YEAR=2014

URL=https://www.frontiersin.org/journals/neural-circuits/articles/10.3389/fncir.2014.00139

DOI=10.3389/fncir.2014.00139

ISSN=1662-5110

ABSTRACT=<p>Microcircuits composed of dendrite-targeting inhibitory interneurons and pyramidal cells (PCs) are fundamental elements of cortical networks, however, the impact of individual interneurons on pyramidal dendrites is unclear. Here, we combine paired recordings and calcium imaging to determine the spatial domain over which single dendrite-targeting interneurons influence PCs in olfactory cortex. We show that a major action of individual interneurons is to inhibit dendrites in a branch-specific fashion.</p>