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REVIEW article

Front. Nanotechnol.
Sec. Biomedical Nanotechnology
Volume 6 - 2024 | doi: 10.3389/fnano.2024.1465429
This article is part of the Research Topic Spotlight on Nanotechnology: Italy View all 4 articles

Advanced techniques and nanotechnologies for point-of-care (POC) testing

Provisionally accepted
Valeria Secchi Valeria Secchi Alice Armanni Alice Armanni Linda Barbieri Linda Barbieri Antonia Bruno Antonia Bruno Alessandro Colombo Alessandro Colombo Sara Fumagalli Sara Fumagalli Ekaterina Kukushkina Ekaterina Kukushkina Roberto Lorenzi Roberto Lorenzi Letizia Marchesi Letizia Marchesi Hind Moukham Hind Moukham Alberto Paleari Alberto Paleari Alessandra Ronchi Alessandra Ronchi Giulia Tomaino Giulia Tomaino Farida Tripodi Farida Tripodi Miriam Colombo Miriam Colombo Laura Sironi Laura Sironi Angelo Monguzzi Angelo Monguzzi *
  • University of Milano-Bicocca, Milan, Italy

The final, formatted version of the article will be published soon.

    Hospitals and other healthcare facilities harbor a complex interplay of microbial pathogens. The correct understanding of pathogens distribution and evolution is therefore crucial for infections control and for the design of effective prevention strategies. In parallel, the integration of cutting-edge nanotechnologies for the early detection and monitoring of these specific target pathogens is considered the most effective approach to face nosocomial infections. In this context, point-of-care (POC) testing, also known as near-patient testing, is becoming increasingly important. In this review we provide a systematic insight into the recent scientific and technological advances in pathogen detection that explore advanced nanotechnologies to realize devices and nanobiosensors, with improved selectivity and sensitivity. In particular, we report on the most diffused and affordable nanotechnologies developed and still developing for POC testing, with the aim to increase the sensitivity, speed and accuracy of pathogens detection in different environments, from intensive care units to outside the laboratory and hospital settings. The text is sub-divided in several sections, each one focused on different type of nanomaterials and techniques actually employed.

    Keywords: Nanotechnology, Nanobiosensors, pathogens, point-of-care, Pathogens detection

    Received: 16 Jul 2024; Accepted: 27 Dec 2024.

    Copyright: © 2024 Secchi, Armanni, Barbieri, Bruno, Colombo, Fumagalli, Kukushkina, Lorenzi, Marchesi, Moukham, Paleari, Ronchi, Tomaino, Tripodi, Colombo, Sironi and Monguzzi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Angelo Monguzzi, University of Milano-Bicocca, Milan, Italy

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.