AUTHOR=Naughton J. R. , Varela J. A. , Connolly T. J. , Shepard S. , Dodge T. E. , Kempa K. , Burns M. J. , Christianson J. P. , Naughton M. J. 

TITLE=Suppression of crosstalk in multielectrode arrays with local shielding

JOURNAL=Frontiers in Nanotechnology

VOLUME=4

YEAR=2022

URL=https://www.frontiersin.org/journals/nanotechnology/articles/10.3389/fnano.2022.948337

DOI=10.3389/fnano.2022.948337

ISSN=2673-3013

ABSTRACT=<p>Electrical crosstalk can constrain the performance of multielectrode arrays in electro- and neurophysiology, in terms of both stimulation and recording. This is especially so at high electrode density, desirable for spatiotemporal mapping of bioelectrical signals from multiple cells. Channel interference due to crosstalk is currently only partially addressed, <italic>via</italic> continuous interleaved sampling or post-data acquisition spike sorting. Here, we show that a locally-shielded electrode architecture significantly suppresses crosstalk, and enables multi-site recording at high electrode density without the need for spike sorting. Arrays of shielded electrodes, prepared by micro- and nanofabrication techniques in a vertically-oriented coaxial geometry, demonstrate at least a 400 times improvement in spatial density over the unshielded case.</p>