AUTHOR=Singh Avtar , Singh Paramjit , Kumar Rajeev , Kaushik Ajeet TITLE=Exploring nanoselenium to tackle mutated SARS-CoV-2 for efficient COVID-19 management JOURNAL=Frontiers in Nanotechnology VOLUME=4 YEAR=2022 URL=https://www.frontiersin.org/journals/nanotechnology/articles/10.3389/fnano.2022.1004729 DOI=10.3389/fnano.2022.1004729 ISSN=2673-3013 ABSTRACT=

Despite ongoing public health measures and increasing vaccination rates, deaths and disease severity caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its new emergent variants continue to threaten the health of people around the world. Therefore, there is an urgent need to develop novel strategies for research, diagnosis, treatment, and government policies to combat the variant strains of SARS-CoV-2. Since the state-of-the-art COVID-19 pandemic, the role of selenium in dealing with COVID-19 disease has been widely discussed due to its importance as an essential micronutrient. This review aims at providing all antiviral activities of nanoselenium (Nano-Se) ever explored using different methods in the literature. We systematically summarize the studied antiviral activities of Nano-Se required to project it as an efficient antiviral system as a function of shape, size, and synthesis method. The outcomes of this article not only introduce Nano-Se to the scientific community but also motivate scholars to adopt Nano-Se to tackle any serious virus such as mutated SARS-CoV-2 to achieve an effective antiviral activity in a desired manner.