AUTHOR=Jia Zhiwei , Wen Tianlin , Zhang Yuning TITLE=Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA JOURNAL=Frontiers in Molecular Neuroscience VOLUME=16 YEAR=2023 URL=https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2023.1277755 DOI=10.3389/fnmol.2023.1277755 ISSN=1662-5099 ABSTRACT=

Tanshinone IIA serves as a coenzyme for certain biochemical reactions, exhibiting various pharmacological effects in the treatment of neurological diseases including spinal cord injury (SCI), however, its working mechanism in the treatment of SCI is not clear. Based on previous research, we believe that tanshinone IIA promotes the survival and repair of nerves after spinal cord injury through its pharmacological effects such as anti-inflammatory, antioxidant, and prevention of cellular apoptosis in the spinal cord.