AUTHOR=Abbasi Asghar , Forsberg Kirsi , Bischof Felix TITLE=The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes JOURNAL=Frontiers in Molecular Neuroscience VOLUME=8 YEAR=2015 URL=https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2015.00021 DOI=10.3389/fnmol.2015.00021 ISSN=1662-5099 ABSTRACT=

In recent years, the ubiquitin-editing enzyme A20 has been shown to control a large set of molecular pathways involved in the regulation of protective as well as self-directed immune responses. Here, we assess the current and putative roles of A20 in inflammatory, vascular and degenerative diseases of the central nervous system and explore future directions of research.