Frontiers in Molecular Medicine

Editorial

Accepted on 23 Jan 2025

Editorial: Neuroinflammatory Aspects in Neurological Disorders

in Molecular Mechanisms of Neurodegeneration

Alipio Pinto
César Fabián Loidl
Jorge Goldstein

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1557546

Review

Accepted on 22 Jan 2025

Epigenetic regulation of TDP-43: potential implications for Amyotrophic Lateral Sclerosis (ALS)

in Molecular Medicine and Cancer Treatment

Degisew Yinur Mengistu
Marta Terribili
Claudia Pellacani
Laura Ciapponi
Marta Marzullo

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1530719

Original Research

Accepted on 20 Jan 2025

Identifying biomarkers of hepatic fatty acid metabolism disorder in sevoflurane-induced brain developmental injury by bioinformatics analysis

in Molecular Mechanisms of Neurodegeneration

Haozheng Yuan
Yuying Lv
Pei Fan
Pengyu Jia
Kui Wang
Kailing Hu
Haogong Sun
Xinlin Chen
Pengbo Zhang

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2025.1369365

Editorial

Published on 09 Jan 2025

Editorial: Gene therapy and genome editing for metabolic liver disorders

in Cell Therapy

Fanny Collaud
Giulia Bortolussi

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1543685

246 views

Brief Research Report

Published on 08 Jan 2025

An artificial transcription factor that activates potent interferon-γ expression in human Jurkat T Cells

in Molecular Mechanisms of Immune Response

Ashley King
Davis Noblitt
Olivia Sherron
Clara Kjerfve
Lydia Pless
Nicholas L. Truex

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1492370

705 views

Original Research

Published on 06 Jan 2025

Immune-checkpoint-inhibitor therapy directed against PD-L1 is tolerated in the heart without manifestation of cardiac inflammation in a preclinical reversible melanoma mouse model

in Molecular Medicine for Cardiology

Caroline Schoenherr
Stefan Pietzsch
Cristina Barca
Franziska E. Müller
Frauke S. Bahr
Martina Kasten
Andre Zeug
Sergej Erschow
Christine S. Falk
Evgeni Ponimaskin

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1487526

447 views

Opinion

Published on 27 Nov 2024

Human-specific gene ARHGAP11B—potentially an additional tool in the treatment of neurodegenerative diseases?

in Molecular Mechanisms of Neurodegeneration

Wieland B. Huttner

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1465647

391 views

Hypothesis and Theory

Published on 18 Sep 2024

DeltaRex-G, tumor targeted retrovector encoding a CCNG1 inhibitor, for CAR-T cell therapy induced cytokine release syndrome

in Molecular Medicine and Cancer Treatment

Grace Haroun
Erlinda M. Gordon

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1461151

937 views

Review

Published on 06 Sep 2024

Role of epigenetic in cancer biology, in hematologic malignancies and in anticancer therapy

in Cell Therapy

Armel Hervé Nwabo Kamdje
Hervet Paulain Dongmo Fogang
Patrice N. Mimche

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1426454

1,703 views

Editorial

Published on 03 Jul 2024

Editorial: Mitochondrial dysfunction affects mechano-energetic coupling in heart failure

in Molecular Medicine for Cardiology

Jan Dudek
Julia Ritterhoff

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1433102

875 views

Original Research

Published on 29 Apr 2024

Tafazzin deficiency causes substantial remodeling in the lipidome of a mouse model of Barth Syndrome cardiomyopathy

in Molecular Medicine for Cardiology

Malte Hachmann
Güntas Gülcan
Ranjithkumar Rajendran
Marcus Höring
Gerhard Liebisch
Akash Bachhuka
Michael Kohlhaas
Christoph Maack
Süleyman Ergün
Jan Dudek

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1389456

2,204 views

Editorial

Published on 27 Feb 2024

Editorial: Celebrating the 200th mendel’s anniversary: gene-targeted diagnostics and therapies for cancer

in Molecular Medicine and Cancer Treatment

Noah Federman
Erlinda M. Gordon
Sant P. Chawla
Frederick L. Hall

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1366963

1,526 views

Review

Published on 01 Feb 2024

Current advances in experimental and computational approaches to enhance CAR T cell manufacturing protocols and improve clinical efficacy

in Cell Therapy

Alfredo S. Colina
Viren Shah
Ravi K. Shah
Tanya Kozlik
Ranjan K. Dash
Scott Terhune
Anthony E. Zamora

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1310002

8,144 views
1 citation

Original Research

Published on 26 Jan 2024

Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood

in Molecular Microbes and Disease

Antony M. Rapulana
Thabo Mpotje
Omolara O. Baiyegunhi
Hlumani Ndlovu
Theresa K. Smit
Timothy D. McHugh
Mohlopheni J. Marakalala

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2024.1345510

2,424 views
1 citation

Original Research

Published on 08 Jan 2024

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)

in Molecular Pathology

Claudia Theys
Tineke Vanderhaeghen
Evelien Van Dijck
Cedric Peleman
Anne Scheepers
Joe Ibrahim
Ligia Mateiu
Steven Timmermans
Tom Vanden Berghe
Sven M. Francque

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2023.1283170

3,046 views
1 citation

Editorial

Published on 04 Jan 2024

Editorial: The role of glial cells in neurodegeneration

in Molecular Mechanisms of Neurodegeneration

Piera Pasinelli
Kathrin Meyer
Laura Ferraiuolo
Robert A. Culibrk
Rita Sattler

Frontiers in Molecular Medicine

doi 10.3389/fmmed.2023.1337286

1,675 views

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Articles

Editorial: Neuroinflammatory Aspects in Neurological Disorders

Epigenetic regulation of TDP-43: potential implications for Amyotrophic Lateral Sclerosis (ALS)

Identifying biomarkers of hepatic fatty acid metabolism disorder in sevoflurane-induced brain developmental injury by bioinformatics analysis

Editorial: Gene therapy and genome editing for metabolic liver disorders

An artificial transcription factor that activates potent interferon-γ expression in human Jurkat T Cells

Immune-checkpoint-inhibitor therapy directed against PD-L1 is tolerated in the heart without manifestation of cardiac inflammation in a preclinical reversible melanoma mouse model

Human-specific gene ARHGAP11B—potentially an additional tool in the treatment of neurodegenerative diseases?

DeltaRex-G, tumor targeted retrovector encoding a CCNG1 inhibitor, for CAR-T cell therapy induced cytokine release syndrome

Role of epigenetic in cancer biology, in hematologic malignancies and in anticancer therapy

Editorial: Mitochondrial dysfunction affects mechano-energetic coupling in heart failure

Tafazzin deficiency causes substantial remodeling in the lipidome of a mouse model of Barth Syndrome cardiomyopathy

Editorial: Celebrating the 200th mendel’s anniversary: gene-targeted diagnostics and therapies for cancer

Current advances in experimental and computational approaches to enhance CAR T cell manufacturing protocols and improve clinical efficacy

Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)

Editorial: The role of glial cells in neurodegeneration