Frontiers in Molecular Biosciences

Original Research

Accepted on 23 Apr 2025

A Glutamine Metabolism Gene Signature with Prognostic and Predictive Value for Colorectal Cancer Survival and Immunotherapy Response

Yinmeng Zhang
He Zhu
Jiawei Fan
Jiahui Zhao
yan xia
Nan Zhang
Hong Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1599141

Original Research

Accepted on 23 Apr 2025

Multi-omics analysis of flavor differences in pectoral muscles between Wuqin 10 duck and Cherry valley duck

Ping Gong
Shengqiang Ye
Xing Chen
Lixia Wang
Yunguo Qian
Mingli Zhai
Yu Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558907

Original Research

Published on 23 Apr 2025

Systematic use of protein free energy changes for classifying variants of uncertain significance: the case of IFT140 in Mainzer-Saldino Syndrome

Macarena Gajardo
José Luis Guerrero
Bárbara Poblete
Esperanza Bayyad
Ignacio Castro
Jorge Maturana
Jaime Tobar
Víctor Faúndes
Paola Krall

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1561380

Original Research

Published on 23 Apr 2025

Successful prediction of LC8 binding to intrinsically disordered proteins sheds light on AlphaFold’s black box

Douglas R. Walker
Gretchen Fujimura
Juan M. Vanegas
Elisar J. Barbar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1531793

125 views

Brief Research Report

Accepted on 22 Apr 2025

Clinical and Molecular Implications of cGAS/STING Signaling in Checkpoint Inhibitor Immunotherapy

Hao Chen
Yang Zhong
Rongjie Feng
Xingyu Zhu
Kang Xu
Mingjie Kuang
Wei Chong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1556736

Review

Accepted on 22 Apr 2025

Engineered Exosomes: A Promising Drug Delivery Platform with Therapeutic Potential

Jinyu Zhang
Genevieve Mo Schwarz
Xuechen Ren
Wen Xie
Haitao Guo
Yong Jiang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1583992

Original Research

Accepted on 22 Apr 2025

Identification of key genes CCL5, PLG, LOX and C3 in clear cell renal cell carcinoma through integrated bioinformatics analysis

Weiming Deng
Xie Zhenwei
Cheng Feng
Yude Hong
Libo Chen
Mingyong Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1587196

Original Research

Accepted on 22 Apr 2025

Perimenopause promotes neuroinflammation in select hippocampal regions in a mouse model of Alzheimer's disease

Roberta Marongiu
Jimcy Platholi
LAIBAIK PARK
Fangmin Yu
Garrett Sommer Sommer
Clara Woods
Teresa A Milner
Michael J Glass

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1597130

Opinion

Published on 22 Apr 2025

Challenges in myeloperoxidase quantification: the inadequacies of current colorimetric approaches

Ian Jhemes Oliveira Sousa
Kerolayne de Melo Nogueira
Ester Miranda Pereira
Rita de Cássia Meneses Oliveira

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1559499

145 views

Brief Research Report

Accepted on 21 Apr 2025

Beyond Serology: Saccharide profiling enables identification of antigenically similar Leptospira and prompts re-evaluation of bacterial lipopolysaccharide evolution

Aleksandra Lewicka
Jan Lyczakowski
Pardyak Laura
Dubniewicz Klaudia
Dariusz Latowski
Arent Zbigniew

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1581587

Correction

Accepted on 21 Apr 2025

Corrigendum: Avenanthramide-C ameliorate doxorubicin-induced hepatotoxicity via modulating Akt/GSK-3β and Wnt-4/β-Catenin pathways in male rats.

Maha Abdullah Alwaili
Amal Abu-Almakarem
Salwa Aljohani
Sahar Alkhodair
Maha Al-Bazi
Thamir Eid
Jehan Alamri
Maysa Mobasher
Norah Algarzae
Arwa Ishaq A Khayyat

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1601841

Original Research

Accepted on 21 Apr 2025

Identification of biomarkers and immune microenvironment associated with heart failure through bioinformatics and machine learning

Jingyun Jin
Shuyan Qin
Fu Qiang
Changzhi Yu
Hongjin Wu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1580880

Original Research

Accepted on 21 Apr 2025

Integrative Multi-omics and Mendelian Randomization Analysis Reveal SPP1 + Tumor-Associated Macrophage-Driven Prognostic Signature for Hepatocellular Carcinoma

Kai Lei
Yichun Lei
Yaoze Wang
Zhixin Ye
Jiawei Liu
Wenhao Chen
Caihong Zhou
Jinmei Tan
Shuxian Chen
Yifan Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1594610

Original Research

Accepted on 21 Apr 2025

Metabolic Insights into Hypoxia Adaptation in Adolescent Athletes at Different Altitudes: A Cross-Sectional Study

Carlos Ramírez-Sánchez
Daniel Pardo-Rodriguez
Erica Mabel Mancera
Lizeth Dayana León Carreño
Dailson Paulucio
Angelo D'Alessandro
Caleb Guedes Santos
Edgar Cristancho
Gustavo Monnerat
Diana Marcela Ramos-Caballero

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1571103

112 views

Review

Accepted on 21 Apr 2025

The significance of calcium ions in cerebral ischemia-reperfusion injury: mechanisms and intervention strategies

Yong-wang Li
Yu Liu
Sheng-Zhen Luo
Xiao-Juan Huang
Yan Shen
Wei-Si Wang
Zhi-Chen Lang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1585758

Original Research

Accepted on 18 Apr 2025

Cuscutae Semen in Depression-Induced Ovarian Dysfunction: Metabolomics with UPLC-QToF-MS in Female Mice

Ying Xie
Zhaoxiang Zeng
Jinrong Zhang
Qiangqiang Han
Chengwu Song
Shuna Jin
Min Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1595602

358 views