Frontiers in Molecular Biosciences

Volume 12 - 2025

Original Research

Accepted on 07 Mar 2025

Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy The metabolome of benign prostate tissues is influenced by nearby tumors of high grade

Ilona Dudka
Pernilla Wikström
Anders Bergh
Gerhard Gröbner

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1426949

Original Research

Accepted on 07 Mar 2025

S100A8/A9 high expression macrophages mediate renal tubular epithelial cells damage in acute kidney injury following acute type A aortic dissection surgery

Xiujuan Cai
Zhigang Wang
Xin Li
Jian Shi
Lu Tang
Jie Yang
Ronghuang Yu
Dongjin Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1530741

Original Research

Accepted on 07 Mar 2025

High-throughput metabolomics exploring the pharmacological effect and mechanism of icariin on rheumatoid arthritis rat based on ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

Peng Zhou
Yushi TIAN
Qianqian Liu
Shouze Ren
Hua Liang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1514882

Original Research

Accepted on 07 Mar 2025

Paritaprevir as a Pan-antiviral Against Different Flaviviruses

Nihar R. Jena
Ramprakash Yadav

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1524951

Original Research

Published on 07 Mar 2025

Rapamycin combined with osimertinib alleviated non-small cell lung cancer by regulating the PARP, Akt/mTOR, and MAPK/ERK signaling pathways

Qingrong Ma
Kai Chen
Haiping Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548810

135 views

Review

Published on 07 Mar 2025

Role of the cytoskeleton in cellular reprogramming: effects of biophysical and biochemical factors

Ekaterina Momotyuk
Nour Ebrahim
Ksenia Shakirova
Erdem Dashinimaev

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1538806

140 views

Original Research

Accepted on 06 Mar 2025

Systematic use of protein free energy changes for classifying variants of uncertain significance: the case of IFT140 in Mainzer-Saldino Syndrome

Macarena Gajardo
José Luis Guerrero
Bárbara Poblete
Esperanza Bayyad
Ignacio Castro
Jorge Maturana
Jaime Tobar
Victor Faundes
Paola Krall

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1561380

Original Research

Accepted on 05 Mar 2025

Computational Analysis of the Structural-Functional Dynamics of a Co-receptor proteoglycan

Francesco Tavanti
Giorgia Brancolini
Roberto Perris

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1549177

Review

Accepted on 05 Mar 2025

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of nonparenchymal cells

Meng Ning
Donghui Lu
Dong Liang
Pei-Gen Ren

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1513993

Original Research

Accepted on 05 Mar 2025

Osteoporotic vertebral fractures and subsequent fractures: Risk factors from a retrospective observational study of patients with osteoporosis

Mingxing Fan
Ran Lu
Jiayuan Wu
Jie Huang
Yanming Fang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558052

Review

Published on 05 Mar 2025

Exploring proinsulin proteostasis: insights into beta cell health and diabetes

Parisima Ghaffarian Zavarzadeh
Kathigna Panchal
Dylan Bishop
Elizabeth Gilbert
Mahi Trivedi
Tovaria Kee
Srivastav Ranganathan
Anoop Arunagiri

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1554717

577 views

Original Research

Published on 04 Mar 2025

Carbon dots derived from Zingiber officinale Rosc (ginger) with hemostatic effects

Wen-Jing Hu
Ai-Qi Yu
Hai-Zheng Bi
Zhao-Jiong Zhang
Zhi-Bin Wang
Meng Wang
Hai-Xue Kuang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1530469

203 views

Original Research

Accepted on 03 Mar 2025

FRONTIERS IN MOLECULAR BIOSCIENCE Highly conserved ion binding sites are not all functionally relevant in mouse KCC4

Lisa Becker
Jens Hausmann
Rieke Wellpott
Anna-Maria Hartmann

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1556250

Original Research

Accepted on 03 Mar 2025

Network Pharmacology Analysis of Lanatoside C: Molecular Targets and Mechanisms in the Treatment of Ulcerative Colitis

Wenjing Zhu
Zhengjie Zhang
XINYUAN WANG

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1552360

Editorial

Accepted on 03 Mar 2025

Editorial: Metabolomics Perspectives for Clinical Medicine: Volume II

Danuta Dudzik
Julia Kuligowski
Víctor González-Ruiz
Hector Gallart-Ayala

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1577050

Volume 11 - 2024

Original Research

Published on 07 Mar 2025

Integrated transcriptomic and metabolomic analysis reveals the effects of EMMPRIN on nucleotide metabolism and 1C metabolism in AS mouse BMDMs

Yun Zhang
Diyuan Zhang
Zulong Xie
Tianli Xia
Lili Zou
Tao Wang
Li Zhong
Zhuo Zeng
Lingying Wang
Guozhu Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1460186

173 views

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Volumes

Volume 12 - 2025

Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy The metabolome of benign prostate tissues is influenced by nearby tumors of high grade

S100A8/A9 high expression macrophages mediate renal tubular epithelial cells damage in acute kidney injury following acute type A aortic dissection surgery

High-throughput metabolomics exploring the pharmacological effect and mechanism of icariin on rheumatoid arthritis rat based on ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

Paritaprevir as a Pan-antiviral Against Different Flaviviruses

Rapamycin combined with osimertinib alleviated non-small cell lung cancer by regulating the PARP, Akt/mTOR, and MAPK/ERK signaling pathways

Role of the cytoskeleton in cellular reprogramming: effects of biophysical and biochemical factors

Systematic use of protein free energy changes for classifying variants of uncertain significance: the case of IFT140 in Mainzer-Saldino Syndrome

Computational Analysis of the Structural-Functional Dynamics of a Co-receptor proteoglycan

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of nonparenchymal cells

Osteoporotic vertebral fractures and subsequent fractures: Risk factors from a retrospective observational study of patients with osteoporosis

Exploring proinsulin proteostasis: insights into beta cell health and diabetes

Carbon dots derived from Zingiber officinale Rosc (ginger) with hemostatic effects

FRONTIERS IN MOLECULAR BIOSCIENCE Highly conserved ion binding sites are not all functionally relevant in mouse KCC4

Network Pharmacology Analysis of Lanatoside C: Molecular Targets and Mechanisms in the Treatment of Ulcerative Colitis

Editorial: Metabolomics Perspectives for Clinical Medicine: Volume II

Volume 11 - 2024

Integrated transcriptomic and metabolomic analysis reveals the effects of EMMPRIN on nucleotide metabolism and 1C metabolism in AS mouse BMDMs