Frontiers in Molecular Biosciences

Original Research

Published on 22 Jan 2025

Diagnostic potential of CDK1 and STAT1 in acute kidney injury associated with gastrointestinal cancers: a bioinformatics-based study

in Molecular Diagnostics and Therapeutics

Qiuwan Wei
Yiqing Shen
Yiren Tian
Yunzhi Ling

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1522246

665 views

Brief Research Report

Published on 22 Jan 2025

Melanoma-derived cytokines and extracellular vesicles are interlinked with macrophage immunosuppression

in Molecular Diagnostics and Therapeutics

Shankar Suman
Wendy K. Nevala
Alexey A. Leontovich
James W. Jakub
Liyi Geng
Sarah A. McLaughlin
Svetomir N. Markovic

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1522717

783 views

Original Research

Published on 22 Jan 2025

Labeling tumor-associated extracellular vesicles with antibody-DNA conjugates for quantitative analysis

in Molecular Diagnostics and Therapeutics

Xiao Du
Hongxiu Li
Shiyi Shen
Chao Tian
Xiaohuan Cao
Xingang Xu
Nan Xu
Shuling Wang
Qingchang Tian

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1531108

681 views

Editorial

Published on 21 Jan 2025

Editorial: Oncolytic virotherapy, volume II

in Molecular Diagnostics and Therapeutics

Ahmed Majeed Al-Shammari
Pier Paolo Piccaluga

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1552643

1,228 views

Original Research

Published on 21 Jan 2025

Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples

in Molecular Diagnostics and Therapeutics

Maxim Sorokin
Vladimir Lyadov
Maria Suntsova
Marat Garipov
Anna Semenova
Natalia Popova
Egor Guguchkin
Rustam Heydarov
Marianna Zolotovskaia
Xiaowen Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1448792

954 views

Original Research

Published on 20 Jan 2025

Metabolic consequences of erastin-induced ferroptosis in human ovarian cancer cells: an untargeted metabolomics study

in Metabolomics

Kaylie I. Kirkwood-Donelson
Alan K. Jarmusch
Carl D. Bortner
Bruce Alex Merrick
Birandra K. Sinha

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1520876

1,491 views

Original Research

Published on 20 Jan 2025

Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes

in Lipids, Membranes and Membranous Organelles

Yunus E. Dogan
Niharika Bala
Erika S. Galban
Russell L. Lewis
Nancy D. Denslow
Sihong Song
Abdel A. Alli

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1485506

896 views

Original Research

Published on 17 Jan 2025

Global trends and emerging insights in BRAF and MEK inhibitor resistance in melanoma: a bibliometric analysis

in Molecular Diagnostics and Therapeutics

Jianhao Bai
Zhongqi Wan
Wanru Zhou
Lijun Wang
Wei Lou
Yao Zhang
Haiying Jin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1538743

1,062 views

Editorial

Published on 17 Jan 2025

Editorial: Metabolomics and transcriptomics in biomarker discovery: mass spectrometric techniques in volatilome research

in Metabolomics

Andras Szeitz
Jens Herbig
Konstantinos A. Kouremenos
Shane Fitzgerald
Steven J. Hallam

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1545016

1,074 views

Original Research

Published on 17 Jan 2025

Plasma proteome fingerprint in kidney diseases

in Molecular Diagnostics and Therapeutics

Kirill S. Nikolsky
Arthur T. Kopylov
Valeriya I. Nakhod
Natalia V. Potoldykova
Dmitry V. Enikeev
Tatiana V. Butkova
Liudmila I. Kulikova
Kristina A. Malsagova
Vladimir R. Rudnev
Denis V. Petrovskiy

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1494779

1,135 views

Original Research

Published on 15 Jan 2025

Predicting patient outcomes with gene-expression biomarkers from colorectal cancer organoids and cell lines

in Molecular Diagnostics and Therapeutics

Alexandra Razumovskaya
Mariia Silkina
Andrey Poloznikov
Timur Kulagin
Maria Raigorodskaya
Nina Gorban
Anna Kudryavtseva
Maria Fedorova
Boris Alekseev
Alexander Tonevitsky

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1531175

1,520 views

Original Research

Published on 15 Jan 2025

First-trimester metabolic profiling of gestational diabetes mellitus: insights into early-onset and late-onset cases compared with healthy controls

in Metabolomics

Danuta Dudzik
Vangeliya Atanasova
Coral Barbas
Jose Luis Bartha

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1452312

1,162 views

Brief Research Report

Published on 13 Jan 2025

Metabolomics insights into doxorubicin and 5-fluorouracil combination therapy in triple-negative breast cancer: a xenograft mouse model study

in Metabolomics

Mai M. Hassanein
Yousra A. Hagyousif
Ruba A. Zenati
Hamza M. Al-Hroub
Farman Matloob Khan
Ahmad Y. Abuhelwa
Karem H. Alzoubi
Nelson C. Soares
Waseem El-Huneidi
Eman Abu-Gharbieh

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1517289

1,190 views

Original Research

Published on 13 Jan 2025

Enhanced intestinal epithelial co-culture model with orbital mechanical stimulation: a proof-of-concept application in food nanotoxicology

in Nanobiotechnology

Mattia Santoni
Giovanni Piccinini
Giovanni Liguori
Maria Roberta Randi
Massimo Baroncini
Liliana Milani
Francesca Danesi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1529027

727 views

Original Research

Published on 09 Jan 2025

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

in Molecular Diagnostics and Therapeutics

Yan Zhang
Xiujuan Chen
Yuan Lin
Xiaoqing Liu
Xiumei Xiong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1504015

1,158 views

Review

Published on 09 Jan 2025

Recent advances of lysine lactylation in prokaryotes and eukaryotes

in Cellular Biochemistry

Wenjuan Zhao
Jiayi Xin
Xin Yu
Zhifang Li
Nan Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1510975

2,766 views