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REVIEW article

Front. Mol. Biosci.
Sec. Molecular Diagnostics and Therapeutics
Volume 11 - 2024 | doi: 10.3389/fmolb.2024.1429852

Advances in understanding the Molecular Mechanisms of Borderline Ovarian Tumors

Provisionally accepted
Shiying Chen Shiying Chen Li Huang Li Huang Meili Liang Meili Liang Yajing Xie Yajing Xie Zhimei Zhou Zhimei Zhou Yumin Ke Yumin Ke *Zhuna Wu Zhuna Wu *
  • The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China

The final, formatted version of the article will be published soon.

    Borderline ovarian tumors (BOTs), which are a special type of epithelial tumor of the ovary, lie between benign and malignant tumors and have low malignant potential. Due to the fact that the early symptoms of these tumors are relatively subtle, they are not easy to diagnose clinically. This study explores advancements in clinical detection methods and provides a comprehensive overview of molecules such as cell migration factors, cell transcription factors, cell damage repair factors, cell cycle regulators, and tumor suppressor genes that are related to the development of BOTs and their related mechanisms in recent years, thus aiming to provide more sensitive, specific, and efficient differential diagnosis and treatment plans for patients to improve their prognosis and survival outcomes.

    Keywords: bot, clinical detection methods, diagnosis, molecular mechanism, Treatment

    Received: 08 May 2024; Accepted: 12 Aug 2024.

    Copyright: © 2024 Chen, Huang, Liang, Xie, Zhou, Ke and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yumin Ke, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China
    Zhuna Wu, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.