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REVIEW article

Front. Mol. Biosci.
Sec. RNA Networks and Biology
Volume 11 - 2024 | doi: 10.3389/fmolb.2024.1382772

Progress and Trends in Myocardial Infarction-Related Long non-coding RNAs: A Bibliometric Analysis

Provisionally accepted
Qingkun Meng Qingkun Meng 1Hao Tan Hao Tan 2Chengfu Wang Chengfu Wang 1Zhijun Sun Zhijun Sun 3*
  • 1 Department of Cardiology, The People's Hospital of China Medical University, Shenyang, China
  • 2 Department of Thoracic and Esophageal Radiotherapy, Liaoning Cancer Hospital & Institute, Shenyang, China
  • 3 Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang, China

The final, formatted version of the article will be published soon.

    Myocardial infarction (MI), a critical condition, substantially affects patient outcomes and mortality rates. Long non-coding RNAs (lncRNAs) play a critical role in the onset and progression of MI. This study aimed to explore the related research on MI-related lncRNAs from a bibliometric perspective.A comprehensive search was conducted on August 7, 2023, using the Web of Science Core Collection (WoSCC) database to compile a dataset of all English-language scientific journals. The search gathered all relevant publications from January 2000 to August 2023. Data on countries, institutions, journals, authors, and keywords were collected, sorted, statistically analyzed, and visualized using CiteSpace 6.2.R4, VOSviewer 1.6.19, an online bibliometric analysis platform (http://bibliometric.com), and the bibliometric package in R-Studio 4.3.1. Articles were screened by two independent reviewers.Between January 2000 and August 2023, a total of 1452 papers were published in the research field. The year with the most publications was 2020, accounting for 256 papers. The publication volume displayed an exponential growth trend. In this domain, China leads in both the number of published papers and total citations, followed by the United States, Germany, Iran, and Italy. The most productive institution is Harbin Medical University (N=144). The European Review for Medical and Pharmacological Sciences had the highest number of publications (N=46), while Circulation Research had the most citations (TC=4537). Research mainly focuses on the cardiovascular system, cellular biology, physiology, etc. The most productive author is Zhang Y. Apart from "Myocardial Infarction" and "LncRNA," the most frequent keywords include "expression," "atherosclerosis," and "apoptosis." Cluster analysis suggests current research themes concentrate on cardiovascular diseases and gene expression, cardiac ischemia/reperfusion injury and protection, expression and proliferation, atherosclerosis and inflammatory response, among others. Keyword bursts indicate recent hot topics as targeting, autophagy, etc.This bibliometric analysis reveals that research on MI-related lncRNAs has rapidly expanded between January 2000 and August 2023, primarily led by China and the United States. Our study provides insights into the features and quality of related publications, as well as the future directions in this research field. There is a long road ahead, highlighting the urgent need for enhanced global academic exchange.

    Keywords: Myocardial infarction (MI), Long non-coding RNAs (lncRNAs), Bibliometric, Web of Science Core Collection, Cluster analysis

    Received: 06 Feb 2024; Accepted: 10 Jul 2024.

    Copyright: © 2024 Meng, Tan, Wang and Sun. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhijun Sun, Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.