AUTHOR=Rajeswaren Vivian , Wong Jeffrey O. , Yabroudi Dana , Nahomi Rooban B. , Rankenberg Johanna , Nam Mi-Hyun , Nagaraj Ram H. 

TITLE=Small Heat Shock Proteins in Retinal Diseases

JOURNAL=Frontiers in Molecular Biosciences

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2022.860375

DOI=10.3389/fmolb.2022.860375

ISSN=2296-889X

ABSTRACT=<p>This review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks. Their role in specific retinal diseases, highlighting their regulation, role in pathogenesis, and possible use as therapeutics, is discussed.</p>