AUTHOR=Carrick William T. , Burks Brandi , Cairns Murray J. , Kocerha Jannet 

TITLE=Noncoding RNA Regulation of Dopamine Signaling in Diseases of the Central Nervous System

JOURNAL=Frontiers in Molecular Biosciences

VOLUME=3

YEAR=2016

URL=https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2016.00069

DOI=10.3389/fmolb.2016.00069

ISSN=2296-889X

ABSTRACT=<p>Dopaminergic neurotransmission mediates a majority of the vital central nervous system functions. Disruption of these synaptic events provokes a multitude of neurological pathologies, including Parkinson's, schizophrenia, depression, and addiction. Growing evidence supports a key role for noncoding RNA (ncRNA) regulation in the synapse. This review will discuss the role of both short and long ncRNAs in dopamine signaling, including bioinformatic examination of the pathways they target. Specifically, we focus on the contribution of ncRNAs to dopaminergic dysfunction in neurodegenerative as well as psychiatric disease.</p>