Original Research

Accepted on 03 Dec 2024

The role of neutrophilia in hyperlactatemia, blood acidosis, impaired oxygen transport, and mortality outcome in critically ill COVID-19 patients

in Cellular Biochemistry

Basma A. Yasseen
Aya A. Elkhodiry
Hajar El-Sayed
Mona Zidan
Azza Kamel
Mohamed A Badawy
Marwa Hamza
Riem M El-Messiery
Mohamed Elansary
Engy Ahmed Abdel-rahman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1510592

Original Research

Published on 03 Dec 2024

The conformation of the nSrc specificity-determining loop in the Src SH3 domain is modulated by a WX conserved sequence motif found in SH3 domains

in Molecular Recognition

Frederick Longshore-Neate
Caroline Ceravolo
Cole Masuga
Elise F. Tahti
Jadon M. Blount
Sarah N. Smith
Jeanine F. Amacher

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1487276

157 views

Original Research

Published on 03 Dec 2024

Investigation of the correlation between AGRN expression and perineural invasion in colon cancer

in Molecular Diagnostics and Therapeutics

Lei Chen
Haijia Zhang
Kaiyue Gao
Fanqi Meng
Funing Yang
Jiannan Li
Lijie Wang
Jiandong Tai

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1510478

Original Research

Accepted on 02 Dec 2024

Biomarker Discovery and Development of Prognostic Prediction Model Using Metabolomic Panel in Breast Cancer Patients: A Hybrid Methodology Integrating Machine Learning and Explainable Artificial Intelligence

in Metabolomics

Fatma Hilal Yagin
Yasin GÖRMEZ
Fahaid AL-Hashem
Irshad Ahmad
Fuzail Ahmad
Luca Paolo Ardigò

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1426964

Review

Accepted on 02 Dec 2024

Application of Machine Learning for Mass Spectrometry-based Multi-omics in Thyroid Diseases

in Metabolomics

Yanan Che
Meng Zhao
Yan Gao
Zhibin Zhang
Xiangyang Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1483326

228 views

Original Research

Accepted on 02 Dec 2024

Disparate molecular mechanisms in cardiac ryanodine receptor channelopathies

in Molecular Diagnostics and Therapeutics

Yadan Zhang
Monika Seidel
Camille Rabesahala De Meritens
Astrid Beckmann
Syeda Ahmed
Melanie Hurtz
F Anthony Lai
Dimitris Parthimos
Spyros Zissimopoulos

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1505698

Original Research

Accepted on 02 Dec 2024

Unveiling and validating biomarkers related to the IL-10 family in chronic sinusitis with nasal polyps: Insights from transcriptomics and single-cell RNA sequencing analysis

in Molecular Diagnostics and Therapeutics

Xinghong Liu
Yi Peng
Ling Guo
Weilan Xiong
Weijiang Liao
Fan Jiangang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1513951

Original Research

Published on 02 Dec 2024

Avenanthramide-C ameliorate doxorubicin-induced hepatotoxicity via modulating Akt/GSK-3β and Wnt-4/β-Catenin pathways in male rats

in Cellular Biochemistry

Maha Abdullah Alwaili
Amal S. Abu-Almakarem
Salwa Aljohani
Sahar Abdulrahman Alkhodair
Maha M. Al-Bazi
Thamir M. Eid
Jehan Alamri
Maysa A. Mobasher
Norah K. Algarza
Arwa Ishaq A. Khayyat

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1507786

200 views

Original Research

Published on 02 Dec 2024

Exploring TAS2R46 biomechanics through molecular dynamics and network analysis

in Biological Modeling and Simulation

Marco Cannariato
Riccardo Fanunza
Eric A. Zizzi
Marcello Miceli
Giacomo Di Benedetto
Marco A. Deriu
Lorenzo Pallante

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1473675

133 views

Original Research

Accepted on 29 Nov 2024

Untargeted Metabolomic Profiling of Gestational Diabetes Mellitus: Insights into Early Diagnosis and Metabolic Pathway Alterations

in Metabolomics

Shereen M. Aleidi
Hiba Al Fahmawi
Reem H Almalki
Maha Al Mogren
Mohammad Alwahsh
Muhammad Mujammami
Michele Costanzo
Anas Abdel Raman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1485587

Review

Accepted on 29 Nov 2024

Effects of Vaccinium-Derived Antioxidants on Human Health: The Past, Present and Future

in Molecular Diagnostics and Therapeutics

Amrita Ghosh
Samir C Debnath
Abir U Igamberdiev

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1520661

Editorial

Published on 29 Nov 2024

Editorial: Diving deeper with metabolomics into animal physiology

in Metabolomics

Dagnachew Hailemariam
Elda Dervishi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1503412

290 views

Original Research

Accepted on 28 Nov 2024

Integrated Multi-Omics Analysis Describes Immune Profiles in Ischemic Heart Failure and Identifies PTN as a Novel Biomarker

in Molecular Diagnostics and Therapeutics

Ting Xiong
Quhuan Li
Yifan Wang
Ying Kong
Hailin Li
Jie Liu
Yueheng Wu
Zhang Fengxia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1524827

Original Research

Accepted on 28 Nov 2024

Independent evolution of oleate hydratase clades in Bacillales reflects molecular convergence

in Molecular Evolution

Robert J Neff
Priscila C Lages
Shannon K Donworth
James D Brien
Christopher D. Radka

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1485485

Methods

Published on 28 Nov 2024

A goldilocks computational protocol for inhibitor discovery targeting DNA damage responses including replication-repair functions

in Molecular Recognition

Davide Moiani
John A. Tainer

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1442267

291 views

Editorial

Published on 28 Nov 2024

Editorial: Serum metabolites in diagnostics and therapeutics

in Metabolomics

Gregorio Peron
Donghai Lin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1528799

122 views

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Articles

The role of neutrophilia in hyperlactatemia, blood acidosis, impaired oxygen transport, and mortality outcome in critically ill COVID-19 patients

The conformation of the nSrc specificity-determining loop in the Src SH3 domain is modulated by a WX conserved sequence motif found in SH3 domains

Investigation of the correlation between AGRN expression and perineural invasion in colon cancer

Biomarker Discovery and Development of Prognostic Prediction Model Using Metabolomic Panel in Breast Cancer Patients: A Hybrid Methodology Integrating Machine Learning and Explainable Artificial Intelligence

Application of Machine Learning for Mass Spectrometry-based Multi-omics in Thyroid Diseases

Disparate molecular mechanisms in cardiac ryanodine receptor channelopathies

Unveiling and validating biomarkers related to the IL-10 family in chronic sinusitis with nasal polyps: Insights from transcriptomics and single-cell RNA sequencing analysis

Avenanthramide-C ameliorate doxorubicin-induced hepatotoxicity via modulating Akt/GSK-3β and Wnt-4/β-Catenin pathways in male rats

Exploring TAS2R46 biomechanics through molecular dynamics and network analysis

Untargeted Metabolomic Profiling of Gestational Diabetes Mellitus: Insights into Early Diagnosis and Metabolic Pathway Alterations

Effects of Vaccinium-Derived Antioxidants on Human Health: The Past, Present and Future

Editorial: Diving deeper with metabolomics into animal physiology

Integrated Multi-Omics Analysis Describes Immune Profiles in Ischemic Heart Failure and Identifies PTN as a Novel Biomarker

Independent evolution of oleate hydratase clades in Bacillales reflects molecular convergence

A goldilocks computational protocol for inhibitor discovery targeting DNA damage responses including replication-repair functions

Editorial: Serum metabolites in diagnostics and therapeutics