ORIGINAL RESEARCH article
Front. Microbiol.
Sec. Virology
Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1594847
Late HIV/AIDS diagnosis among people living with HIV in Wuhan in 2023
Provisionally accepted
- Wuhan Centre for Disease Prevention and Control, Wuhan, China
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Late HIV diagnosis is defined as presenting for care with a CD4 count <350 cells/μl or an AIDS-defining event, and remains a significant challenge in preventing and controlling HIV/AIDS in the world. To explore the late diagnosis of HIV in Wuhan, we retrospectively analyzed the late diagnosis among the newly identified people living with HIV in 2023. Of 383 newly diagnosed individuals with HIV infection, 260 (67.89%) were diagnosed late and their CD4 counts were less than 350 cells/μl, of which 135 (35.25%) were in advanced HIV diseases and their CD4 count was less than 200 cells/μl. Compared to those diagnosed promptly, the population with late HIV diagnosis had a higher viral load, older age, and lower CD/CD8 ratio, and they were more likely to be men who have sex with men (MSM) and farmers and be diagnosed through voluntary counseling & testing (VCT) or clinical patients. These findings indicated a high rate of late HIV diagnosis in Wuhan, suggesting the need for more attention and more targeted measures toward earlier diagnosis in the population.
Keywords: Late HIV diagnosis, Advanced HIV diseases, CD4 counts, Men who have sex with men (MSM), Wuhan
Received: 17 Mar 2025; Accepted: 24 Apr 2025.
Copyright: © 2025 Tang, Du, KONG, Liu, Zhu, Xie and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Man-Qing Liu, Wuhan Centre for Disease Prevention and Control, Wuhan, China
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