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PERSPECTIVE article
Front. Microbiol.
Sec. Virology
Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1576308
Commentary on: Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin
Provisionally accepted- 1 University of Cologne, Cologne, Germany
- 2 Institute for Virology, University Hospital of Cologne, Cologne, North Rhine-Westphalia, Germany
- 3 Department of Kinesiology, College of Health and Human Sciences, Kansas State University, Manhattan, Kansas, United States
Son et al. (2024) (Son et al., 2024) examined the evolutionary role of betapapillomaviruses (β-HPVs) in skin homeostasis. Using the mouse papillomavirus model, findings reveal that papillomavirus-specific immunity protects against UV-induced mutations by targeting p53-mutant cells. This work suggests β-HPVs enhance tissue integrity, offering insights into strategies for preventing and managing cutaneous carcinoma.
Keywords: HPV - human papillomavirus, beta HPV, skin homeostasis, Skin carcinogenesis, Skin Cancer Mouse Model
Received: 13 Feb 2025; Accepted: 26 Feb 2025.
Copyright: © 2025 Akgül and Wallace. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Baki Akgül, University of Cologne, Cologne, Germany
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