REVIEW article

Front. Microbiol.

Sec. Microbial Symbioses

Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1558567

Effects and molecular mechanism of endophytic elicitors on the accumulation of secondary metabolites in medicinal plants

Provisionally accepted
Yaxuan  WangYaxuan WangNana  ChenNana ChenXinying  ZhongXinying ZhongZhaogao  LiZhaogao LiLin  LiLin LiDelin  XuDelin Xu*
  • Zunyi Medical University, Zunyi, China

The final, formatted version of the article will be published soon.

Endophytes in medicinal plants possess significant biological value since they have in them the ability to provide elicitors crucial in regulating plant growth as also different secondary metabolites. This review emphasizes the effective ability of endophytic fungi to induce their hosts, explains the biological mechanisms of using endophytic fungi to enhance the accumulation of secondary metabolites in medicinal plant cultures, and summarizes the extensive application of endophytic fungi elicitors in medicinal plant cultivation. The main goal of this article is to clarify the mechanism and important role of endophytic elicitors in the production of natural drugs. This information will be helpful for scientific researchers in controlling the quality of medicinal materials, prioritizing endophytic resources, and achieving a circular and sustainable development and production of natural medicine.

Keywords: Endophytic, Secondary metabolite, biosynthesis, Biological mechanism, medicinal plant

Received: 10 Jan 2025; Accepted: 24 Apr 2025.

Copyright: © 2025 Wang, Chen, Zhong, Li, Li and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Delin Xu, Zunyi Medical University, Zunyi, China

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