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ORIGINAL RESEARCH article
Front. Microbiol.
Sec. Microbe and Virus Interactions with Plants
Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1551436
This article is part of the Research Topic Bacillus and Pseudomonas as Plant Friends: Molecular, Physiological and Ecological Interactions View all 7 articles
Optimizing Surfactin yield in Bacillus velezensis BN to Enhance Biocontrol Efficacy and Rhizosphere Colonization
Provisionally accepted- Lanzhou Jiaotong University, Lanzhou, China
Surfactins, lipopeptide-type biosurfactants which combine interesting physicochemical properties and biological activities, secreted by plant growth-promoting rhizobacteria (PGPR), have garnered attention for their dual functionality in promoting plant growth and controlling plant diseases, highlighting their potential as biopesticides. However, the practical application of surfactin is constrained by the low yield in natural strains.This study focused on optimizing the culture conditions for Bacillus velezensis BN, a strain with exceptional biocontrol properties, to enhance its surfactin yield. The study revealed that nitrogen sources and amino acid supplementation were critical factors that resulted in a remarkable 5.94-fold increase in surfactin yield compared to the baseline. Furthermore, a positive correlation was established between surfactin yield and biocontrol efficacy: Enhanced surfactin yield was associated with improved antifungal activity, biofilm formation, and rhizosphere colonization capacity of B. velezensis BN on potato plantlets. These findings provide new insights into the practical application of surfactin and establish a scientific foundation for the development of innovative and eco-friendly antifungal agents suitable for agricultural use.
Keywords: PGPR, Surfactin, biocontrol, Biofilms, colonization
Received: 25 Dec 2024; Accepted: 20 Feb 2025.
Copyright: © 2025 Liu, Zheng, Wang, Wang, Wang and Tian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yongqiang Tian, Lanzhou Jiaotong University, Lanzhou, China
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