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REVIEW article
Front. Microbiol.
Sec. Microorganisms in Vertebrate Digestive Systems
Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1488732
The Role of Microbiota in the Chronic Prostatitis/Chronic Pelvis Pain Syndrome
Provisionally accepted- 1 Anhui Medical University, Hefei, China
- 2 Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
- 3 The Institute of Urology, Anhui Medical University, Hefei, Anhui Province, China
Chronic prostatitis/Chronic pelvis pain syndrome (CP/CPPS), a kind of frequent urinary condition among adult males, has caused a lot of inconvenience to patients in life, whose pathogenesis is unclear. Current evidence suggests that it is most likely to be an autoimmune disease. Symbiotic microbes, a highly diverse biological community that harbors trillions of microbes in each region of the human body, have gradually made people realize their important role in immune regulation, material metabolism, and health maintenance. In recent years, increasing studies have shown a connection between microbiota and CP/CPPS. In view of this, we performed this review to summarize the literature pertaining to microbiota and its association with the pathophysiological mechanism of CP/CPPS. In addition, we gleaned the latest progress in the therapeutic strategy of CP/CPPS that related to microbiota regulation in order to offer new perspectives on the management of CP/CPPS.
Keywords: microbiota, CP/CPPS, Pathogenesis, Treatment Microbiota, Treatment
Received: 30 Aug 2024; Accepted: 24 Feb 2025.
Copyright: © 2025 Deng, Yue, Niu, Zhang, Liang and Du. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Li Zhang, Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China
Chaozhao Liang, Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China
Hexi Du, Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China
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