Skip to main content

REVIEW article

Front. Microbiol.
Sec. Infectious Agents and Disease
Volume 15 - 2024 | doi: 10.3389/fmicb.2024.1515291

Reviewing advancement in Mycoplasma pneumoniae P30 adhesin protein provides insights for future diagnosis and treatment

Provisionally accepted
Shuihong Li Shuihong Li *Yingying Zuo Yingying Zuo Ru Zhang Ru Zhang
  • University of South China, Hengyang, Hunan Province, China

The final, formatted version of the article will be published soon.

    Mycoplasma pneumoniae is a major pathogen that causes upper and lower respiratory tract infections in children, adolescents, and elderly individuals and can lead to pneumonia, intrapulmonary and extrapulmonary complications, and respiratory sequelae. M. pneumoniae must adhere to respiratory epithelial cells of a host for infection. The P1 and P30 proteins, as two adhesin proteins of M. pneumoniae, have attracted extensive attention from many researchers. In this paper, we present the latest research progress on the P30 protein in terms of structure and mutation typing, physiological function, clinical serological diagnosis and vaccine development in a literature review. This study deepens our knowledge on the pathogenesis of M. pneumoniae and is useful for diagnosing and preventing M. pneumoniae infection.

    Keywords: Mycoplasma pneumoniae, P30 protein, Adhesion, diagnosis, Vaccine

    Received: 22 Oct 2024; Accepted: 28 Nov 2024.

    Copyright: © 2024 Li, Zuo and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Shuihong Li, University of South China, Hengyang, 421001, Hunan Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.