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SYSTEMATIC REVIEW article

Front. Microbiol.
Sec. Infectious Agents and Disease
Volume 15 - 2024 | doi: 10.3389/fmicb.2024.1507340
This article is part of the Research Topic Immune Insights into Orthopedic Infections: Mechanisms, Biomarkers, and Prevention View all articles

Research trends and focus of Prosthetic Joint Infections from 2013 to 2023: bibliometric and visualization studies

Provisionally accepted
Liwen Zhang Liwen Zhang 1Diqian Zhao Diqian Zhao 1Lei Duan Lei Duan 1Wenzhe Bai Wenzhe Bai 1*Bing Yan Bing Yan 2
  • 1 First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China
  • 2 Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China

The final, formatted version of the article will be published soon.

    BACKGROUND: Postoperative infections in artificial joints provide considerable difficulties in the field of orthopaedics, especially after joint replacement procedures. These infections rank among the most severe postoperative consequences, frequently leading to treatment ineffectiveness and reduced quality of life for surgery patients. Consequently, it is crucial to acquire knowledge about worldwide research trends in this area in order to educate clinical practices and improve therapeutic techniques. This work exploits bibliometric analysis to investigate the present state, developing patterns, and main areas of focus in research on artificial joint infection. OBJECTIVE: To analyze the research trends, hotspots, and international collaborations on artificial joint infections worldwide from 2013 to 2023. METHODS: Extractions of raw data were made from the WoSCC (Web of Science Core Collection) database. Detailed information collected includes the quantity of publications, authors, citations, publication year, h-index, references, country/region, journal, and keywords. Analysis of the data was conducted using VOSviewer version 1.6.10.0 and CiteSpace version 6.3.R1. RESULTS: A total of 1,799 articles published between 2013 and 2023 were included in this analysis, showing a steady increase in publication with the United States leading at 553 articles. Infection rates and topics such as biofilm formation and antimicrobial resistance were highly cited, with Mayo Clinic contributing 65 articles as the most prolific institution. CONCLUSION: Research on biofilm infections, antibiotic resistance, and new biomarkers is a key focus, particularly on disrupting biofilms and enhancing diagnostics. There's growing attention in biomarkers like α-defensins and exosomal miRNAs for PJI diagnosis, pointing to new clinical uses. Studies on antimicrobial-coated prosthetics and topical agents are also gaining importance in treatment strategies.

    Keywords: artificial joint infection1, bibliometrics2, biofilm3, Antibiotic resistance4, infection diagnosis5 antimicrobial coating6, infection control strategies7

    Received: 10 Oct 2024; Accepted: 25 Nov 2024.

    Copyright: © 2024 Zhang, Zhao, Duan, Bai and Yan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Wenzhe Bai, First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.