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MINI REVIEW article

Front. Microbiol.
Sec. Infectious Agents and Disease
Volume 15 - 2024 | doi: 10.3389/fmicb.2024.1486792
This article is part of the Research Topic Research Advances and Challenges in Emerging and Re-Emerging Viral Diseases View all 7 articles

The Latest Advancements in Sosuga virus (SOSV) Research

Provisionally accepted
Nathan M. Markarian Nathan M. Markarian 1Levon Abrahamyan Levon Abrahamyan 2*
  • 1 Faculté de pharmacie, Université de Montréal, Montreal, Quebec, Canada
  • 2 Swine and Poultry Infectious Diseases Research Center (CRIPA) and Research Group on Infectious Diseases in Production Animals (GREMIP), Faculty of Veterinary Medicine, University of Montreal, QC, Saint-Hyacinthe, Quebec, Canada

The final, formatted version of the article will be published soon.

    The last 60 years have seen the emergence of several zoonotic viruses, some of which originate from bats. Among these are Nipah virus (NiV) and Marburg virus (MV), Ebola virus, which have high case fatality rates, posing significant public health risks. In 2012, another zoonotic paramyxovirus from bats, known as Sosuga Virus (SOSV), was discovered in a hospitalized biologist who had returned from a trip to Africa. Given the potential public health threats of the SOSV, investigating its pathogenesis, epidemiology and developing antiviral strategies are crucial to control possible future outbreaks. Thus, in this review, we explore the latest advancements in understanding SOSV since its discovery, focusing on its pathogenesis, animal models and the development of antiviral strategies. By examining the current literature, this review aims to provide a comprehensive overview to guide future studies and help public health efforts in better mitigating potential SOSV outbreaks.

    Keywords: Sosuga virus, Paramixovirus, Viral spillover, Rousettus aegyptiacus, Egyptian rousette bat, Viral zoonoses, Emerging viral disease

    Received: 26 Aug 2024; Accepted: 17 Oct 2024.

    Copyright: © 2024 Markarian and Abrahamyan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Levon Abrahamyan, Swine and Poultry Infectious Diseases Research Center (CRIPA) and Research Group on Infectious Diseases in Production Animals (GREMIP), Faculty of Veterinary Medicine, University of Montreal, QC, Saint-Hyacinthe, Quebec, Canada

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.