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ORIGINAL RESEARCH article

Front. Microbiol.
Sec. Microbiotechnology
Volume 15 - 2024 | doi: 10.3389/fmicb.2024.1472992

Preparation of safflower fermentation solution and study on its biological activity

Provisionally accepted
Nan Tang Nan Tang Xiaoqing Xu Xiaoqing Xu Zhenyu Guo Zhenyu Guo Xiangyu Meng Xiangyu Meng Guoqiang Qian Guoqiang Qian *He Li He Li *
  • Guangdong Pharmaceutical University, Guangzhou, China

The final, formatted version of the article will be published soon.

    In this study, a fermentation solution of safflower was developed by using microbial fermentation technology. The optimal fermentation conditions were determined by single factor test and response surface method. Then the antioxidant and anti-inflammatory effects of safflower fermentation liquid were verified by cell and zebrafish models. Finally, the safety of safflower fermentation liquid was evaluated by eye irritation test of cosmetics. Results The flavonoid of safflower was increased after fermentation, which had anti-inflammatory and antioxidant properties.

    Keywords: Safflower1, Yeast2, fermentation3, antioxidant4, anti-inflammatory5

    Received: 30 Jul 2024; Accepted: 26 Sep 2024.

    Copyright: © 2024 Tang, Xu, Guo, Meng, Qian and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Guoqiang Qian, Guangdong Pharmaceutical University, Guangzhou, China
    He Li, Guangdong Pharmaceutical University, Guangzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.