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SYSTEMATIC REVIEW article

Front. Microbiol.
Sec. Microbial Physiology and Metabolism
Volume 15 - 2024 | doi: 10.3389/fmicb.2024.1463909
This article is part of the Research Topic Bacteriocins and other Ribosomally Synthesised and Post-translationally modified Peptides (RiPPs) as modulators of the microbiome View all 9 articles

Editorial: Bacteriocins and Ribosomally Synthesised Post-Translationally Modified Peptides (RiPPs) as modulators of the microbiome

Provisionally accepted
Harsh Mathur Harsh Mathur 1*Des Field Des Field 2Caitriona M. Guinane Caitriona M. Guinane 3Máire Begley Máire Begley 3Mathew Upton Mathew Upton 4Hilario C. Mantovani Hilario C. Mantovani 5Paul D. Cotter Paul D. Cotter 1*
  • 1 Moorepark Food Research Centre, Teagasc Food Research Centre (Ireland), Fermoy, Ireland
  • 2 School of Microbiology, College of Science, Engineering and Food Science, University College Cork, Cork, Ireland
  • 3 Munster Technological University, Cork, County Cork, Ireland
  • 4 University of Plymouth, Plymouth, England, United Kingdom
  • 5 University of Wisconsin-Madison, Madison, Wisconsin, United States

The final, formatted version of the article will be published soon.

    This Research Topic (RT) entitled ‘Bacteriocins and Ribosomally Synthesised Post-Translationally modified Peptides (RiPPs) as modulators of the microbiome’ focussed on various aspects of these peptides. It includes seven research articles that cover a variety of related areas, including the testing the impact of a range of bacteriocins on a simplified human intestinal microbiota, the investigation of a regulator involved in bacteriocin production, elucidation of the mechanism of action of a lantibiotic, optimisation of the heterologous production of circular bacteriocins and utilisation of in silico tools to identify novel bacteriocins, amongst other topics. The RT also includes a timely review article relating to the use of bacteriocin like inhibitory substances (BLIS) to strategically shape the oral microbiota. Here we briefly describe these studies and the insights they provide with respect to the ability of RiPPs to modulate microbiomes.

    Keywords: Bacteriocins, Peptides, microbiome, Modulating, antimicrobials

    Received: 12 Jul 2024; Accepted: 05 Aug 2024.

    Copyright: © 2024 Mathur, Field, Guinane, Begley, Upton, Mantovani and Cotter. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Harsh Mathur, Moorepark Food Research Centre, Teagasc Food Research Centre (Ireland), Fermoy, Ireland
    Paul D. Cotter, Moorepark Food Research Centre, Teagasc Food Research Centre (Ireland), Fermoy, Ireland

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.