Skip to main content

ORIGINAL RESEARCH article

Front. Microbiol.
Sec. Food Microbiology
Volume 15 - 2024 | doi: 10.3389/fmicb.2024.1439522

Antimicrobial resistance and genomic analysis of Vibrio parahaemolyticus isolates from foodborne outbreaks, Huzhou, China, 2019-2023

Provisionally accepted
Wei Yan Wei Yan Lei Ji Lei Ji Fenfen Dong Fenfen Dong Liping Chen Liping Chen Yuan Rui Yuan Rui Peng Zhang Peng Zhang *
  • Huzhou center for disease control and prevention, Huzhou, China

The final, formatted version of the article will be published soon.

    Objective: The purpose of this study was to investigate the epidemiological and genomic characteristics of Vibrio parahaemolyticus(V. parahaemolyticus) isolates from outbreaks in Huzhou, China. Methods: To analyze the epidemiological data on V. parahaemolyticus outbreaks reported in Huzhou from 2019 to 2023. A total of 70 V. parahaemolyticus outbreaks isolates were collected. The antibiotic resistance, serotypes, molecular typing andgenomic characteristics of these isolates were analyzed. Results: Most outbreaks of V. parahaemolyticus infection occured in the summer, and the majority of outbreaks occur in restaurants and rural banquet. High resistance rates were observed for AMP (24.29%), followed by TET (15.71%) and SXT (15.71%). The newly emerged serotype O10:K4 became dominant from 2021 to 2023, with most isolates belonging to ST3. The resistance gene blaCARB was frequently detected among these isolates.The Pulsed field gel electrophoresis (PFGE) and whole-genome single-nucleotide polymorphisms (wgSNPs) effectively differentiated the nine outbreaks. Conclusion: The newly emerged serotype O10:K4 became dominant from 2021 to the present, and most of isolates were ST3. PFGE and WGS technologies provided reliable methods for typing and identification of V. parahaemolyticus for outbreaks. Key words: Vibrio parahaemolyticus, foodborne disease, outbreak, PFGE, WGS

    Keywords: Vibrio parahaemolyticus, Foodborne disease, outbreak, PFGE, WGS

    Received: 28 May 2024; Accepted: 27 Aug 2024.

    Copyright: © 2024 Yan, Ji, Dong, Chen, Rui and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Peng Zhang, Huzhou center for disease control and prevention, Huzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.