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REVIEW article
Front. Microbiol.
Sec. Systems Microbiology
Volume 15 - 2024 |
doi: 10.3389/fmicb.2024.1409128
This article is part of the Research Topic The Microbial Link: Exploring Oral and Gut Microbiome Connections View all articles
Traditional Chinese Medicine to Improve Immune Imbalance of Asthma : Focus on the Adjustment of gut microbiota
Provisionally accepted- 1 College of Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
- 2 Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
- 3 School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
Asthma, being the prevailing respiratory ailment globally, remains enigmatic in terms of its pathogenesis. In recent times, the advancement of traditional Chinese medicine pertaining to the intestinal microbiota has yielded a plethora of investigations, which have substantiated the potential of traditional Chinese medicine in disease prevention and treatment through modulation of the intestinal microbiota. Both animal models and clinical trials have unequivocally demonstrated the indispensable role of the intestinal microbiota in the pathogenesis of asthma. This article presents a summary of the therapeutic effects of traditional Chinese medicine in the context of regulating gut microbiota and its metabolites, thereby achieving immune regulation and inhibiting airway inflammation associated with asthma. It elucidates the mechanism by which traditional Chinese medicine modulates the gut microbiota to enhance asthma management, offering a scientific foundation for the utilization of traditional Chinese medicine in the treatment of asthma.
Keywords: Asthma, Effective components of traditional Chinese medicine, Chinese herbal medicine formula, short-chain fatty acids, lipopolysaccharide
Received: 29 Mar 2024; Accepted: 10 Sep 2024.
Copyright: © 2024 Lu, Li, Men, Xu, Chen, Yan, Gai, Zhang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ke Lu, College of Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
Chen Li, College of Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
Bin Xu, Shandong University of Traditional Chinese Medicine, Jinan, 250355, Shandong Province, China
Yang Chen, Shandong University of Traditional Chinese Medicine, Jinan, 250355, Shandong Province, China
Peizheng Yan, School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, Shandong Province, China
Zhibo Gai, Shandong University of Traditional Chinese Medicine, Jinan, 250355, Shandong Province, China
Qingxiang Zhang, College of Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
Lu Zhang, College of Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
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