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SYSTEMATIC REVIEW article

Front. Microbiol.
Sec. Systems Microbiology
Volume 15 - 2024 | doi: 10.3389/fmicb.2024.1401597
This article is part of the Research Topic Animal Models, Gut Microbiota and Brain Diseases View all 21 articles

Influential articles in autism and gut microbiota: Bibliometric profile and research trends

Provisionally accepted
Jiangbo Ying Jiangbo Ying 1Melvyn Weibin Zhang Melvyn Weibin Zhang 1Ker-Chiah Wei Ker-Chiah Wei 1Sunny H Wong Sunny H Wong 2*Mythily Subramaniam Mythily Subramaniam 1*
  • 1 Institute of Mental Health, Singapore, Singapore
  • 2 Nanyang Technological University, Singapore, Singapore

The final, formatted version of the article will be published soon.

    Objective: Autism spectrum disorder (ASD) is a common neurodevelopmental disorder.Increasing evidence suggests that it is potentially related to gut microbiota, but no prior bibliometric analysis has been performed to explore the most influential works in the relationships between ASD and gut microbiota. In this study, we conducted an in-depth analysis of the most-cited articles in this field, aiming to provide insights to the existing body of research and guide future directions.Methods: A search strategy was constructed and conducted in the Web of Science Database to identify the 100 most-cited papers in ASD and gut microbiota. The Biblioshiny software was used to analyze and visualize the relevant information, including citation counts, country distributions, authors, journals, and thematic analysis. Correlation and comparison analyses were performed using SPSS software.The top 100 influential manuscripts were published between 2000 and 2021, with a total citation of 40 662. The average number of citations annually increased over the years and was significantly correlated to the year of publication (r = 0.481, p < 0.01, Spearman's rho test). The United States was involved in the highest number of publications (n = 42). The number of publications in the journal was not significantly related to the journal's latest impact factor (r = 0.016, p > 0.05, Spearman's rho test). Co-occurrence network and thematic analysis identified several important areas, such as microbial metabolites of short-chain fatty acids and overlaps with irritable bowel syndrome.This bibliometric analysis provides the key information of the most influential studies in the area of ASD and gut microbiota, and suggests the hot topics and future directions. The findings of this study can serve as a valuable reference for researchers and policymakers, guiding the development and implementation of the scientific research strategies in this area. Table 1. The 100 most-cited articles in autism spectrum disorder and gut microbiota.

    Keywords: bibliometric analysis, autism, Gut Microbiota, Research trends, citations

    Received: 16 Apr 2024; Accepted: 27 Dec 2024.

    Copyright: © 2024 Ying, Zhang, Wei, Wong and Subramaniam. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Sunny H Wong, Nanyang Technological University, Singapore, 639798, Singapore
    Mythily Subramaniam, Institute of Mental Health, Singapore, Singapore

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.