Wenzhe Hao
1,2*
Lin Huang
1,2
Xuejun Li
3*The final, formatted version of the article will be published soon.
SYSTEMATIC REVIEW article
Front. Microbiol.
Sec. Microorganisms in Vertebrate Digestive Systems
Volume 15 - 2024 |
doi: 10.3389/fmicb.2024.1377541
Novel endoscopic techniques for the diagnosis of Gastric Helicobacter pylori infection: a systematic review and network meta-analysis
Provisionally accepted- 1 Anhui University of Chinese Medicine, Hefei, China
- 2 Graduate School, Anhui University of Chinese Medicine, Hefei, Anhui Province, China
- 3 Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, Anhui Province, China
- 4 Anhui Medical University, Hefei, Anhui Province, China
- 5 School of Public Health, Anhui Medical University, Hefei, Anhui Province, China
Objective: This study aimed to conduct a network meta-analysis to compare the diagnostic efficacy of diverse novel endoscopic techniques for detecting gastric Helicobacter pylori infection. Methods: From inception to August 2023, literature was systematically searched across Pubmed, Embase, and Web of Science databases. Cochrane's risk of bias tool assessed the methodological quality of the included studies. Data analysis was conducted using the R software, employing a ranking chart to determine the most effective diagnostic method comprehensively. Convergence analysis was performed to assess the stability of the results. Results: The study encompassed 36 articles comprising 54 observational studies, investigating 14 novel endoscopic techniques and involving 7230 patients diagnosed with gastric H. pylori infection. Compared with the gold standard, the comprehensive network meta-analysis revealed the superior diagnostic performance of two new endoscopic techniques, Magnifying blue laser imaging endoscopy (M-BLI) and high-definition magnifying endoscopy with i-scan (M-I-SCAN). Specifically, M-BLI demonstrated the highest ranking in both sensitivity (SE) and positive predictive value (PPV), ranking second in negative predictive value (NPV) and fourth in specificity (SP). M-I-SCAN secured the top position in NPV, third in SE and SP, and fifth in PPV. Conclusions: After thoroughly analyzing the ranking chart, we conclude that M-BLI and M-I-SCAN stand out as the most suitable new endoscopic techniques for diagnosing gastric H. pylori infection.
Keywords: Novel endoscopic techniques, gastric, Helicobacter pylori infection, Meta-analysis, diagnosis
Received: 27 Jan 2024; Accepted: 02 Aug 2024.
Copyright: © 2024 Hao, Huang, Li and Jia. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Wenzhe Hao, Anhui University of Chinese Medicine, Hefei, China
Xuejun Li, Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, 230061, Anhui Province, China
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