AUTHOR=Gao Qian , He Jianfu , Wang Jin , Yan Yonghui , Liu Lei , Wang Zuo , Shen Weijun , Wan Fachun TITLE=Effects of dietary D-lactate levels on rumen fermentation, microflora and metabolomics of beef cattle JOURNAL=Frontiers in Microbiology VOLUME=Volume 15 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1348729 DOI=10.3389/fmicb.2024.1348729 ISSN=1664-302X ABSTRACT=Excessive intake of lactate caused by improper use of silage in animal husbandry has adverse effects on rumen fermentation, such as rumen acidosis. The speed of absorption and metabolism of D-lactate in rumen epithelial cells was slower than that of L-lactate, making D-lactate more prone to accumulate and induce rumen acidosis. Therefore, this study was dietary D-lactate into volatile fatty acids increased the energy supply of beef cattle. However, it also increased the ruminal CH4 emissions and the relative abundance of opportunistic pathogen Escherichia-Shigella in beef cattle.