AUTHOR=Cheng Chaoyuan , Li Guoliang , Yang Xifu , Zhao Jidong , Liu Jing , Zheng Aihua , Zhang Zhibin TITLE=High diversity, close genetic relatedness, and favorable living conditions benefit species co-occurrence of gut microbiota in Brandt’s vole JOURNAL=Frontiers in Microbiology VOLUME=15 YEAR=2024 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1337402 DOI=10.3389/fmicb.2024.1337402 ISSN=1664-302X ABSTRACT=Introduction

Revealing factors and mechanisms in determining species co-existence are crucial to community ecology, but studies using gut microbiota data are still lacking.

Methods

Using gut microbiota data of 556 Brandt’s voles from 37 treatments in eight experiments, we examined the relationship of species co-occurrence of gut microbiota in Brandt’s voles (Lasiopodomys brandtii) with genetic distance (or genetic relatedness), community diversity, and several environmental variables.

Results

We found that the species co-occurrence index (a larger index indicates a higher co-occurrence probability) of gut microbiota in Brandt’s voles was negatively associated with the genetic distance between paired ASVs and the number of cohabitating voles in the experimental space (a larger number represents more crowding social stress), but positively with Shannon diversity index, grass diets (representing natural foods), and non-physical contact within an experimental space (representing less stress).

Discussion

Our study demonstrated that high diversity, close genetic relatedness, and favorable living conditions would benefit species co-occurrence of gut microbiota in hosts. Our results provide novel insights into factors and mechanisms that shape the community structure and function of gut microbiota and highlight the significance of preserving the biodiversity of gut microbiota.