AUTHOR=Mo Guodong , Hu Bowen , Wei Ping , Luo Qingbin , Zhang Xiquan 

TITLE=The Role of Chicken Prolactin, Growth Hormone and Their Receptors in the Immune System

JOURNAL=Frontiers in Microbiology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2022.900041

DOI=10.3389/fmicb.2022.900041

ISSN=1664-302X

ABSTRACT=<p>Prolactin (PRL) and growth hormone (GH) exhibit important roles in the immune system maintenance. In poultry, PRL mainly plays its roles in nesting, hatching, and reproduction, while GH is primarily responding to body weight, fat formation and feed conversion. In this review, we attempt to provide a critical overview of the relationship between PRL and GH, PRLR and GHR, and the immune response of poultry. We also propose a hypothesis that PRL, GH and their receptors might be used by viruses as viral receptors. This may provide new insights into the pathogenesis of viral infection and host immune response.</p>