AUTHOR=Romeo-Oliván Ana , Chervin Justine , Breton Coralie , Lagravère Thierry , Daydé Jean , Dumas Bernard , Jacques Alban 

TITLE=Comparative Transcriptomics Suggests Early Modifications by Vintec® in Grapevine Trunk of Hormonal Signaling and Secondary Metabolism Biosynthesis in Response to Phaeomoniella chlamydospora and Phaeoacremonium minimum

JOURNAL=Frontiers in Microbiology

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2022.898356

DOI=10.3389/fmicb.2022.898356

ISSN=1664-302X

ABSTRACT=Species from the genus Trichoderma are of great interest in modern agriculture due to their well-known antifungal abilities. Recent studies have shown that Trichoderma spp are able to induce plant resistance against different phytopathogens. Here, we investigated the transcriptomic response of grapevine trunk to Vintec®, a Trichoderma atroviride SC1-based commercial formulation for biological control of grapevine trunk diseases which allows a decrease of wood colonization. The aim of the study was to understand whether the presence of the biocontrol agent (BCA) Vintec® modifies the response in the trunk to Phaeoacremonium minimum and Phaeomoniella chlamydospora, two esca-associated fungal pathogens. Transcriptional regulation analysis identified clusters of co-regulated genes showing a different transcriptomic reprogramming in response to infection in the absence or the presence of Vintec®. On one hand, our results showed that Vintec® differentially modulates the expression of putative genes involved in hormonal signaling, especially the ones of auxin signaling.  On the other hand, most significant gene expression modifications were observed among secondary metabolism-related genes, especially regarding phenylpropanoid metabolism and stilbene biosynthesis. Together, our results suggest that the BCA Vintec® induces wood responses which can counteract disease development.