AUTHOR=Pessoa Rafael Bastos Gonçalves , Oliveira Weslley Felix de , Correia Maria Tereza dos Santos , Fontes Adriana , Coelho Luana Cassandra Breitenbach Barroso 

TITLE=Aeromonas and Human Health Disorders: Clinical Approaches

JOURNAL=Frontiers in Microbiology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2022.868890

DOI=10.3389/fmicb.2022.868890

ISSN=1664-302X

ABSTRACT=<p>The genus <italic>Aeromonas</italic> comprises more than 30 Gram-negative bacterial species and naturally inhabitants from aquatic environments. These microorganisms, commonly regarded as pathogens of fish and several other animals, have been gaining prominence on medical trial due to its ability to colonize and infect human beings. Besides water, <italic>Aeromonas</italic> are widely spreaded on most varied sources like soil, vegetables, and food; Although its opportunistic nature, they are able to cause infections on immunocompromised or immunocompetent patients. <italic>Aeromonas</italic> species regarded as potential human pathogens are usually <italic>A. hydrophila</italic>, <italic>A. caviae</italic>, and <italic>A. veronii</italic> biovar <italic>sobria</italic>. The main clinical manifestations are gastrointestinal tract disorders, wound, and soft tissue infections, as well as septicemia. Regarding to antibiotic responses, the bacteria present a diversified susceptibility profile and show inherence resistance to ampicillin. <italic>Aeromonas</italic>, as an ascending genus in microbiology, has been carefully studied aiming comprehension and development of methods for detection and medical intervention of infectious processes, not fully elucidated in medicine. This review focuses on current clinical knowledge related to human health disorders caused by <italic>Aeromonas</italic> to contribute on development of efficient approaches able to recognize and impair the pathological processes.</p>