AUTHOR=Lemaire Coralie , Le Gallou Brice , Lanotte Philippe , Mereghetti Laurent , Pastuszka Adeline TITLE=Distribution, Diversity and Roles of CRISPR-Cas Systems in Human and Animal Pathogenic Streptococci JOURNAL=Frontiers in Microbiology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2022.828031 DOI=10.3389/fmicb.2022.828031 ISSN=1664-302X ABSTRACT=
Streptococci form a wide group of bacteria and are involved in both human and animal pathologies. Among pathogenic isolates, differences have been highlighted especially concerning their adaptation and virulence profiles. CRISPR-Cas systems have been identified in bacteria and many streptococci harbor one or more systems, particularly subtypes I-C, II-A, and III-A. Since the demonstration that CRISPR-Cas act as an adaptive immune system in