AUTHOR=Jiang Min , Yang Chao , Kwan Patrick S. L. , Zhang Liping , Fan Hang , Jin Yujuan , Sun Lifang , Chen Hongyu , Li Baisheng , Chen Qiuxia , Wu Yarong , Guo Yan , Shi Yuanguo , Liao Min , Shi Xiaolu , Liu Jianping , Jiang Lijuan , Cai Rui , Deng Yinhua , Sun Qun , Yang Ruifu , Zhang Qiaoli , Cui Yujun , Hu Qinghua TITLE=Rapid Multilateral and Integrated Public Health Response to a Cross-City Outbreak of Salmonella Enteritidis Infections Combining Analytical, Molecular, and Genomic Epidemiological Analysis JOURNAL=Frontiers in Microbiology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2022.772489 DOI=10.3389/fmicb.2022.772489 ISSN=1664-302X ABSTRACT=
On September 21, 2019, the Shenzhen and Dongguan Centers for Disease Control and Prevention received notification of a large cluster of suspected gastroenteritis involving primarily children who sought medical care at hospitals throughout two adjacent cities in China, Shenzhen, and Dongguan. A joint outbreak response was promptly initiated across jurisdictions in a concerted effort between clinical microbiologists, epidemiologists, and public health scientists. Concurrently, multiplex PCRs were used for rapid laboratory diagnosis of suspected cases; epidemiological investigations were conducted to identify the outbreak source, complemented by near real-time multicenter whole-genome analyses completed within 34 h. Epidemiological evidence indicated that all patients had consumed egg sandwiches served on September 20 as snacks to children and staff at a nursery in Dongguan, located near Shenzhen.