Gut microbiome plays a crucial role in maintaining human health and is influenced by food intake, age, and other factors.
In this study based in Korea, we examined the bacterial taxonomic composition of the gut microbiota in infants (≤ 1 year), toddlers (1–<4 years), and school-aged children (4–13 years) and compared them with those of healthy adults to investigate the microbiota changes in early life and their association with the resistome. We used whole metagenome sequences obtained by Illumina HiSeq sequencing and clinical information of 53 healthy children, and sequence data of 61 adults from our previous study.
Our results indicate that the bacterial proportion of the gut in the population ranging from infants to adults forms three clusters: the
In conclusion, our results highlighted that a delayed persistence of the