AUTHOR=Yang Xiaobing , Liu Hai , Zhang Yanxiong , Shen Xihui TITLE=Roles of Type VI Secretion System in Transport of Metal Ions JOURNAL=Frontiers in Microbiology VOLUME=12 YEAR=2021 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2021.756136 DOI=10.3389/fmicb.2021.756136 ISSN=1664-302X ABSTRACT=

The type VI secretion system (T6SS) is a transmembrane protein nanomachine employed by many gram-negative bacteria to directly translocate effectors into adjacent cells or the extracellular milieu, showing multiple functions in both interbacterial competition and bacteria-host interactions. Metal ion transport is a newly discovered T6SS function. This review summarizes the identified T6SS functions and highlights the features of metal ion transport mediated by T6SS and discusses its regulation.