AUTHOR=Zhou Diao , Zhao Ying , Li Jing , Ravichandran Vinothkannan , Wang Leli , Huang Qiuyun , Chen Cang , Ni Hengjia , Yin Jia 

TITLE=Effects of Phytic Acid-Degrading Bacteria on Mineral Element Content in Mice

JOURNAL=Frontiers in Microbiology

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2021.753195

DOI=10.3389/fmicb.2021.753195

ISSN=1664-302X

ABSTRACT=<p>Trace minerals are extremely important for balanced nutrition, growth, and development in animals and humans. Phytic acid chelation promotes the use of probiotics in nutrition. The phytic acid-degrading strain <italic>Lactococcus lactis</italic> psm16 was obtained from swine milk by enrichment culture and direct plate methods. In this study, we evaluated the effect of the strain psm16 on mineral element content in a mouse model. Mice were divided into four groups: basal diet, 1% phytic acid, 1% phytic acid + psm16, 1% phytic acid + 500 U/kg commercial phytase. Concentrations of acetic acid, propionic acid, butyric acid, and total short-chain fatty acids were significantly increased in the strain psm16 group compared to the phytic acid group. The concentrations of copper (<italic>p</italic> = 0.021) and zinc (<italic>p</italic> = 0.017) in liver, calcium (<italic>p</italic> = 0.000), manganese (<italic>p</italic> = 0.000), and zinc (<italic>p</italic> = 0.000) in plasma and manganese (<italic>p</italic> = 0.010) and zinc (<italic>p</italic> = 0.022) in kidney were significantly increased in psm16 group, while copper (<italic>p</italic> = 0.007) and magnesium (<italic>p</italic> = 0.001) were significantly reduced. In conclusion, the addition of phytic acid-degrading bacteria psm16 into a diet including phytic acid can affect the content of trace elements in the liver, kidney, and plasma of mice, counteracting the harmful effects of phytic acid.</p>