AUTHOR=Chang De , Sharma Lokesh , Dela Cruz Charles S. , Zhang Dong 

TITLE=Clinical Epidemiology, Risk Factors, and Control Strategies of Klebsiella pneumoniae Infection

JOURNAL=Frontiers in Microbiology

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2021.750662

DOI=10.3389/fmicb.2021.750662

ISSN=1664-302X

ABSTRACT=<p><italic>Klebsiella</italic> species cause infections at multiple sites, including lung, urinary tract, bloodstream, wound or surgical site, and brain. These infections are more likely to occur in people with preexisting health conditions. <italic>Klebsiella pneumoniae</italic> (<italic>K. pneumoniae</italic>) has emerged as a major pathogen of international concern due to the increasing incidences of hypervirulent and carbapenem-resistant strains. It is imperative to understand risk factors, prevention strategies, and therapeutic avenues to treat multidrug-resistant <italic>Klebsiella</italic> infections. Here, we highlight the epidemiology, risk factors, and control strategies against <italic>K. pneumoniae</italic> infections to highlight the grave risk posed by this pathogen and currently available options to treat <italic>Klebsiella</italic>-associated diseases.</p>