AUTHOR=Devi Priti , Khan Azka , Chattopadhyay Partha , Mehta Priyanka , Sahni Shweta , Sharma Sachin , Pandey Rajesh TITLE=Co-infections as Modulators of Disease Outcome: Minor Players or Major Players? JOURNAL=Frontiers in Microbiology VOLUME=12 YEAR=2021 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2021.664386 DOI=10.3389/fmicb.2021.664386 ISSN=1664-302X ABSTRACT=
Human host and pathogen interaction is dynamic in nature and often modulated by co-pathogens with a functional role in delineating the physiological outcome of infection. Co-infection may present either as a pre-existing pathogen which is accentuated by the introduction of a new pathogen or may appear in the form of new infection acquired secondarily due to a compromised immune system. Using diverse examples of co-infecting pathogens such as Human Immunodeficiency Virus,