AUTHOR=Wang Beibei , Yang Huayi , Sun Jianan , Dou Chuhao , Huang Jian , Guo Feng-Biao 

TITLE=BioMaster: An Integrated Database and Analytic Platform to Provide Comprehensive Information About BioBrick Parts

JOURNAL=Frontiers in Microbiology

VOLUME=12

YEAR=2021

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2021.593979

DOI=10.3389/fmicb.2021.593979

ISSN=1664-302X

ABSTRACT=<p>Synthetic biology seeks to create new biological parts, devices, and systems, and to reconfigure existing natural biological systems for custom-designed purposes. The standardized BioBrick parts are the foundation of synthetic biology. The incomplete and flawed metadata of BioBrick parts, however, are a major obstacle for designing genetic circuit easily, quickly, and accurately. Here, a database termed BioMaster <ext-link ext-link-type="uri" xlink:href="http://www.biomaster-uestc.cn" xmlns:xlink="http://www.w3.org/1999/xlink">http://www.biomaster-uestc.cn</ext-link> was developed to extensively complement information about BioBrick parts, which includes 47,934 items of BioBrick parts from the international Genetically Engineered Machine (iGEM) Registry with more comprehensive information integrated from 10 databases, providing corresponding information about functions, activities, interactions, and related literature. Moreover, BioMaster is also a user-friendly platform for retrieval and analyses of relevant information on BioBrick parts.</p>