AUTHOR=Angelini Claudio , Vizzini Alfredo , Justo Alfredo , Bizzi Alberto , Davoli Paolo , Kaya Ertuğrul 

TITLE=First Report of a Neotropical Agaric (Lepiota spiculata, Agaricales, Basidiomycota) Containing Lethal α-Amanitin at Toxicologically Relevant Levels

JOURNAL=Frontiers in Microbiology

VOLUME=11

YEAR=2020

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2020.01833

DOI=10.3389/fmicb.2020.01833

ISSN=1664-302X

ABSTRACT=<p>A recent collection of <italic>Lepiota spiculata</italic> from the Dominican Republic is presented here. Macro- and micromorphological features of <italic>L. spiculata</italic> are described in detail, and its evolutionary (phylogenetic) position within <italic>Lepiota</italic> sect. <italic>Ovisporae</italic>, in the subincarnata/brunneoincarnata clade, is assessed on the basis of a combined nrLSU + nrITS + <italic>rpb2</italic> + <italic>tef1</italic> analysis. Additionally, high levels of deadly amatoxins were detected and quantified in <italic>L. spiculata</italic> for the first time by HPLC analysis; in particular, α-amanitin was found at concentrations up to approximately 4 mg/g dry weight, which render <italic>L. spiculata</italic> a potentially lethal mushroom, if ingested.</p>