AUTHOR=Papaianni Marina , Paris Debora , Woo Sheridan L. , Fulgione Andrea , Rigano Maria Manuela , Parrilli Ermenegilda , Tutino Maria L. , Marra Roberta , Manganiello Gelsomina , Casillo Angela , Limone Antonio , Zoina Astolfo , Motta Andrea , Lorito Matteo , Capparelli Rosanna 

TITLE=Plant Dynamic Metabolic Response to Bacteriophage Treatment After Xanthomonas campestris pv. campestris Infection

JOURNAL=Frontiers in Microbiology

VOLUME=11

YEAR=2020

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2020.00732

DOI=10.3389/fmicb.2020.00732

ISSN=1664-302X

ABSTRACT=<p>Periodic epidemics of black rot disease occur worldwide causing substantial yield losses. <italic>Xanthomonas campestris</italic> pv. <italic>campestris</italic> (<italic>Xcc</italic>) represents one of the most common bacteria able to cause the above disease in cruciferous plants such as broccoli, cabbage, cauliflower, and <italic>Arabidopsis thaliana</italic>. In agriculture, several strategies are being developed to contain the <italic>Xanthomona</italic>s infection. The use of bacteriophages could represent a valid and efficient approach to overcome this widespread phenomenon. Several studies have highlighted the potential usefulness of implementing phage therapy to control plant diseases as well as <italic>Xcc</italic> infection. In the present study, we characterized the effect of a lytic phage on the plant <italic>Brassica oleracea</italic> var. <italic>gongylodes</italic> infected with <italic>Xcc</italic> and, for the first time, the correlated plant metabolic response. The results highlighted the potential benefits of bacteriophages: reduction of bacterium proliferation, alteration of the biofilm structure and/or modulation of the plant metabolism and defense response.</p>