AUTHOR=Wang Hailong , Xin Xiu , Zheng Congyi , Shen Chao 

TITLE=Single-Cell Analysis of Foot-and-Mouth Disease Virus

JOURNAL=Frontiers in Microbiology

VOLUME=11

YEAR=2020

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2020.00361

DOI=10.3389/fmicb.2020.00361

ISSN=1664-302X

ABSTRACT=<p>With the rapid development of single-cell technologies, the mechanisms underlying viral infections and the interactions between hosts and viruses are starting to be explored at the single-cell level. The foot-and-mouth-disease (FMD) virus (FMDV) causes an acute and persistent infection that can result in the break-out of FMD, which can have serious effects on animal husbandry. Single-cell techniques have emerged as powerful approaches to analyze virus infection at the resolution of individual cells. In this review, the existing single-cell studies examining FMDV will be systematically summarized, and the central themes of these studies will be presented.</p>