AUTHOR=Wang Zhilong , Lu Wanhang , Zhang Yiling , Zou Feng , Jin Zhigang , Zhao Tiejun 

TITLE=The Hippo Pathway and Viral Infections

JOURNAL=Frontiers in Microbiology

VOLUME=10

YEAR=2020

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2019.03033

DOI=10.3389/fmicb.2019.03033

ISSN=1664-302X

ABSTRACT=<p>The Hippo signaling pathway is a novel tumor suppressor pathway, initially found in <italic>Drosophila.</italic> Recent studies have discovered that the Hippo signaling pathway plays a critical role in a wide range of biological processes, including organ size control, cell proliferation, cancer development, and virus-induced diseases. In this review, we summarize the current understanding of the biological feature and pathological role of the Hippo pathway, focusing particularly on current findings in the function of the Hippo pathway in virus infection and pathogenesis.</p>