AUTHOR=Wang Lili , Liang Ruiying , Gao Yaning , Li Yanbai , Deng Xiaoqian , Xiang Rong , Zhang Yina , Ying Tianlei , Jiang Shibo , Yu Fei 

TITLE=Development of Small-Molecule Inhibitors Against Zika Virus Infection

JOURNAL=Frontiers in Microbiology

VOLUME=10

YEAR=2019

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2019.02725

DOI=10.3389/fmicb.2019.02725

ISSN=1664-302X

ABSTRACT=<p>In recent years, the outbreak of infectious disease caused by Zika virus (ZIKV) has posed a major threat to global public health, calling for the development of therapeutics to treat ZIKV disease. Here, we have described the different stages of the ZIKV life cycle and summarized the latest progress in the development of small-molecule inhibitors against ZIKV infection. We have also discussed some general strategies for the discovery of small-molecule ZIKV inhibitors.</p>