Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice
- 1Department of Biomedical Sciences and Pathobiology, Center for Molecular Medicine and Infectious Diseases, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, United States
- 2Department of Biomedical Sciences, Virginia Tech Carilion School of Medicine, Roanoke, VA, United States
A Corrigendum on
Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice
by Freudenberger Catanzaro, K. C., Champion, A. E., Mohapatra, N., Cecere, T., and Inzana, T. J. (2017). Front. Microbiol. 8:935. doi: 10.3389/fmicb.2017.00935
In the original article, there was a mistake in the legend for Figure 6 as published. Figure 6 has 5 lanes, but only 4 are described in the legend. The lane that is not described is lane 3, which should list “3, F. novicida Δ1212–1218[1212-1213+].” As stated the description of lanes 3 and 4 are also wrong, as they should be listed as lanes 4 and 5. The correct legend appears below. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
“Figure 6 | Carbohydrate and protein content of urea extracts from F. novicida and LVS strains. All strains were subcultured in CDMB and grown on CDMA at 32°C to enhance putative CLC production. The surface material was extracted using 1 M urea, and the crude CLC extracts were analyzed for carbohydrate content by the anthrone assay and for protein content by the BCA assay. The carbohydrate content of the extract from F. novicida Δ11212–1218_P10 contained significantly less carbohydrate than that of F. novicida_P10 (p = 0.02). The protein content between subcultured strains of F. novicida or between strains of LVS was not statistically different. Lanes: 1, F. novicida_P10; 2, F. novicida Δ11212–1218_P10; 3, F. novicida Δ1212–1218[1212–1213+]; 4, LVS_P10; 5, LVSΔ1422-1423_P10. Different letters above the bars indicate significant differences between the means when one-way ANOVA and Tukey's post-hoc were performed (p < 0.05). Identical uppercase letters indicate that there is no significant difference between the means. The value of bar marked with “A” is significantly different from the values of bars marked with “B” or “C.” The values of bars marked “AB” are not statistically different from the values of bars marked with “A” or with “B,” but are statistically different from a bar marked with “C.””
Keywords: Francisella novicida, capsule-like complex, virulence in mice, tularemia, glycosylation, protective immunity
Citation: Freudenberger Catanzaro KC, Champion AE, Mohapatra N and Cecere T and Inzana TJ (2019) Corrigendum: Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice. Front. Microbiol. 10:1090. doi: 10.3389/fmicb.2019.01090
Received: 29 April 2019; Accepted: 30 April 2019;
Published: 15 May 2019.
Approved by:
Frontiers Editorial Office, Frontiers Media SA, SwitzerlandCopyright © 2019 Catanzaro, Champion, Mohapatra, Cecere and Inzana. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Thomas J. Inzana, Thomas.Inzana@liu.edu