AUTHOR=Rossato Luana , Colombo Arnaldo Lopes 

TITLE=Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity?

JOURNAL=Frontiers in Microbiology

VOLUME=9

YEAR=2018

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2018.03081

DOI=10.3389/fmicb.2018.03081

ISSN=1664-302X

ABSTRACT=<p><italic>Candida auris</italic> has emerged globally as a multidrug-resistant (MDR) medical care-associated fungal pathogen. Recent reports have demonstrated that <italic>C. auris</italic> usually expresses fewer virulence factors than does <italic>Candida albicans</italic>. However, the tendency of <italic>C. auris</italic> transmission within and between healthcare facilities is unique among <italic>Candida</italic> spp. and is possibly promoted by virulence and pathogenicity factors that facilitate skin colonization and environmental persistence. To understand the ability of this yeast to cause disease, we herein discuss several virulence and pathogenicity aspects of <italic>C. auris.</italic></p>